Official Peptides provides VIP (Vasoactive Intestinal Peptide) at verified research purity with independent third-party HPLC documentation. We ship cold-pack from the US with same-day dispatch and maintain consistent stock. Researchers studying neuropeptides, immune modulation, and autonomic physiology trust Official Peptides for accurate peptide identification and reliable fulfillment.
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide expressed throughout the central and peripheral nervous system, immune cells, and gastrointestinal tract. It signals through VPAC1 and VPAC2 receptors to produce vasodilation, smooth muscle relaxation, and potent immunomodulatory effects. Research has examined VIP in the context of inflammatory bowel disease, pulmonary arterial hypertension, autoimmune conditions, circadian rhythm regulation, and neurological protection. For research use only; not FDA-approved as a standalone therapeutic agent.
Q: What immunomodulatory effects has VIP research documented?
A: VIP is a potent anti-inflammatory neuropeptide. Research has shown it inhibits production of pro-inflammatory cytokines (TNF-α, IL-6, IL-12) from macrophages and dendritic cells while promoting Th2 and regulatory T-cell phenotypes. In autoimmune research models including collagen-induced arthritis and experimental autoimmune encephalomyelitis, VIP administration has demonstrated protective effects.
Q: Why is VIP studied in pulmonary hypertension research?
A: VIP is a potent pulmonary vasodilator and has been found to be deficient in lung tissue of patients with pulmonary arterial hypertension. Inhaled VIP was studied in clinical trials for PAH, and research continues into its vasoprotective and anti-proliferative effects on pulmonary vascular smooth muscle as a mechanistic tool.
Q: How should VIP be stored and handled to maintain activity?
A: Lyophilized VIP is stable at 2-8°C for up to 24 months. Reconstitute in 0.1% BSA solution or other protein-containing buffer to minimize adsorption to plastic surfaces, as VIP can adhere to labware at low concentrations. Once reconstituted, use within 7 days for optimal activity.
Order Vasoactive Intestinal Peptide (VIP) from Official Peptides for verified purity, US-based fulfillment, and quality documentation on every order. Secure checkout, free shipping over $150, and same-day dispatch available.
For Research Use Only. This compound is intended strictly for in vitro laboratory research by qualified scientists. Not for human consumption. Not FDA approved. Keep out of reach of children.
We don't just claim purity — we prove it. Every batch of VIP (Vasoactive Intestinal Peptide) (5mg) is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
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