Official Peptides stocks Humanin at research-grade purity with independent third-party HPLC verification on every batch. We ship cold-pack from the US with same-day dispatch on qualifying orders. Researchers studying mitochondrial-derived peptides and cytoprotective biology choose Official Peptides for our documentation standards and consistent inventory.
Humanin is a 21-amino-acid mitochondria-derived peptide (MDP) encoded within the 16S rRNA region of the mitochondrial genome. First identified in 2001 in a screen for protective factors against Alzheimer’s-related neuronal death, Humanin has since been studied for cytoprotective, anti-apoptotic, and metabolic effects in preclinical models. Research has examined its interactions with insulin signaling, IGFBP-3, and its effects on cellular survival pathways. Humanin levels have been shown to decline with age. For research use only; not approved for human therapeutic application.
Q: What distinguishes Humanin from other mitochondrial-derived peptides?
A: Humanin was the first identified mitochondrial-derived peptide and remains the most extensively studied MDP. Unlike MOTS-C, which primarily affects metabolic pathways in skeletal muscle and adipose tissue, Humanin research has focused heavily on neuroprotection, anti-apoptosis, and cardiovascular cytoprotection. Both are encoded in mitochondrial DNA but target different physiological processes.
Q: What cytoprotective mechanisms has Humanin research examined?
A: Research has documented Humanin’s ability to inhibit Bax-mediated apoptosis, reduce ER stress, and activate JAK2/STAT3 signaling pathways associated with cell survival. Studies have also examined its protective effects in cardiomyocytes under ischemia-reperfusion conditions and in neuronal models of beta-amyloid toxicity.
Q: Is batch-specific documentation available for Humanin orders?
A: Yes. Every Humanin batch is independently verified via HPLC and mass spectrometry. Certificates of analysis are available on request for all purchases from Official Peptides.
Order research-grade Humanin from Official Peptides for verified purity, US-based shipping, and quality documentation on every order. Free shipping over $150. Add to cart and check out securely.
For Research Use Only. This compound is intended strictly for in vitro laboratory research by qualified scientists. Not for human consumption. Not FDA approved. Keep out of reach of children.
We don't just claim purity — we prove it. Every batch of Humanin (5mg) is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
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