Larazotide (20mg)

Why Buy Larazotide from Official Peptides

Official Peptides offers Larazotide (AT-1001) at verified research purity with independent third-party HPLC documentation. We ship from the US with same-day dispatch and cold pack packaging. Researchers investigating intestinal permeability and tight junction biology trust Official Peptides for accurate identification, quality documentation, and consistent stock availability.

Larazotide Research Profile

Larazotide acetate (AT-1001) is a synthetic octapeptide derived from a protein in Vibrio cholerae that modulates tight junction function in intestinal epithelium. It has been studied as an antagonist of zonulin, a protein that regulates intestinal permeability. Clinical research has examined Larazotide in the context of celiac disease, where tight junction dysregulation and increased intestinal permeability are implicated in gluten-triggered immune responses. Multiple clinical trials have assessed its effects on gut barrier integrity. For research use only.

Product Specifications

• Purity: ≥99% (HPLC verified)
• Format: Lyophilized powder
• Quantity: 5mg per vial
• Storage: Store at 2-8°C; protect from light and humidity
• Shipping: USPS Priority Mail with cold pack; ships within 1 business day

Frequently Asked Questions

Q: What is Larazotide’s mechanism of action in research models?
A: Larazotide acts as a tight junction regulator by antagonizing zonulin-mediated tight junction opening. In research models, it has been shown to reduce intestinal permeability and limit translocation of luminal antigens across the epithelial barrier, which is a mechanism of interest in autoimmune and inflammatory conditions involving the gut.

Q: Has Larazotide been tested in human clinical trials?
A: Yes. Multiple Phase II clinical trials have examined Larazotide in celiac disease patients. Some trials showed positive effects on gut permeability markers and symptom reduction, though regulatory approval has not been achieved. Research continues in academic and clinical settings.

Q: Is a certificate of analysis available for Larazotide?
A: Yes. Every Larazotide batch sold by Official Peptides is independently verified by HPLC and mass spectrometry. Certificates of analysis are available upon request or included with your order.

Order Larazotide Online

Order Larazotide from Official Peptides for verified purity, US-based shipping, and quality documentation on every order. Secure checkout, free shipping over $150, and same-day dispatch available.

For Research Use Only. This compound is intended strictly for in vitro laboratory research by qualified scientists. Not for human consumption. Not FDA approved. Keep out of reach of children.